Rasburicase Injection

What is this medicine?

RASBURICASE (ras BURE i kase) breaks down uric acid in the blood. It is used to prevent and to treat high levels of uric acid caused by cancer treatment.

How should I use this medicine?

This medicine is for infusion into a vein. It is given by a health care professional in a hospital or clinic setting.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 1 month old for selected conditions, precautions do apply.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • blue color to lips or nailbeds

  • breathing problems

  • chest pain, tightness

  • confusion

  • fast, irregular heartbeat

  • feeling faint or lightheaded, falls

  • low blood pressure

  • seizures

  • unusually weak or tired

  • yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • abdominal pain

  • constipation

  • diarrhea

  • fever

  • headache

  • nausea, vomiting

  • swelling of the ankles, feet, hands

What may interact with this medicine?

Interactions have not been studied.

Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What if I miss a dose?

This does not apply.

Where should I keep my medicine?

This drug is given in a hospital or clinic and will not be stored at home.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • G6PD deficiency

  • history of anemia

  • history of blood transfusion

  • an unusual or allergic reaction to rasburicase, yeast, mannitol, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Your condition will be monitored carefully while you are receiving this medicine. You will need to have regular blood tests during your treatment.

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